before professionals

4Smile Medical and Dental Center


Wellness mission

What for many was utopia, for us was the true mission. Create a multifunctional structure where specialists from different medical disciplines could operate. A mission that took shape, gradually more and more, from the idea of Dr. De Simone, the first great supporter of the potential of our small territory and the enhancement of true talents and the success of the project.

We have always worked to offer a solid and valid point of reference to our patients, where, together with the care of the body, the noblest part of our profession could find space: help, advice, closeness, caring.

Our strongest points:
  • We have set up our project in a context of continuous dialogue: dialogue with the patient, advised and accompanied in different clinical areas; dialogue between us professionals, committed, today more than ever, in a personal and professional growth open to the needs and expectations of our small and large patients.
  • We are very proud of our commitment on the territory, as a multifunctional pole and reference structure for many. We are strongly aware of the great responsibility we have towards the person, even before the patient, in all his phases of life, from childhood to old age.
  • We strongly believe that the union and the dialogue between different specialized medical cultures can offer the territory a valid response in terms of proximity and completeness; to us professionals, a fertile habitat where to cultivate and increase skills in a context of continuous training.

Charter of Services

Ethical Code

Professional Insurance


Dr. Nicola De Simone

To contribute to the realisation of quality dentistry in a small provincial town in southern Italy. This was ‘my dream’ when I set up my first practice in 1985. To take care not only of the teeth, but to take care of the person as a whole, putting prevention first and offering, in a single location, innovation and technology.

Dental Staff

The safety of being in good hands: professionals from different medical sectors work closely together to ensure you have an excellent health service.

Dr. Giuseppe Musiello


Master in Oral Surgery level II. Specialized at UCAM (Catholic University Sant’Antonio di Murcia in Spain) in Oral Surgery, Periodontology and Implantology.
Dr. Giuseppe De Simone


Dr. Michele Melillo


He graduated with honours from the Polytechnic University of Marche and specialised in oral surgery at the G. D’Annunzio University in Chieti.

Dr. Mastrangelo Andrea

Surgery, Implantology and Periodontology

Graduated in Dentistry and Dental Prosthetics from the ‘G.D’Annunzio’ University of Chieti. He has participated in numerous refresher and advanced courses in Implantology and Implant Prosthetics in Italy and abroad, in particular at the Universidad Complutense in Madrid.
Luna Bonaventura

Dental practice assistant

Medical and Front Office Staff

Dr.ssa Mina Leccese


Degree in medicine and surgery from the University of Bologna, specialising in paediatrics.

Dr. Francesco Cifariello
Dr.ssa Rosanna Parente


Cognitive Psychotherapist, EMDR therapist, graduated with honours in 2006 from the ‘G. d’Annunzio’ University of Chieti. Specialised in Cognitive and Cognitive-behavioural Psychotherapy at “Studi Cognitivi” in San Benedetto del Tronto.

Dr. Pierpaolo Canè


He graduated in Medicine and Surgery at the University of Bologna and later specialised in Orthopaedics and Traumatology at the University of Ancona.

Dr.ssa Natascia D'Ettorres


Maria Rosaria Petta